micro array images

Micro Array Features

The square locations on this Affymetrix array are called "features," and each feature holds millions of identical DNA strands called "probes." The probes are built like semiconductor chips, one layer at a time. (Image courtesy of Affymetrix.)

Hybridization (Pairing)

The human DNA sample, which has been replicated millions of times and fragmented into short pieces, is washed over the micro array. The red balls depict biotin molecules that were adhered to the fragments, which "swim" around the probes for up to 16 hours. During that time, some strands will pair with the probes (the hybridization process). (Image courtesy of Affymetrix.)

Detection

The array is rinsed and washed with a fluorescent stain that clings to the biotin on the strands of the human sample that remain. A laser causes them to glow, and the DNA is analyzed (genotyped) based on which probes on the array they mated with. (Images courtesy of Affymetrix.)

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